Alpha-herpesvirus axon-to-cell spread involves limited virion transmission New research suggests that just a few individual herpes simplex virus particles attack a skin cell in the initial stage of an outbreak, producing a bottleneck in which the infection may be vulnerable to medical treatment. Unlike most viruses that spread to fresh cells by bombarding them with millions of particles, herpes virus type 1 – a virus that causes cold sores and genital lesions – requires just a few viral contaminants to infect a epidermis cell in the first stage of cool sore formation, Princeton University researchers reported this month in the Proceedings of the National Academy of Sciences. ‘The fact that just a few virus particles are participating is astonishing because these viruses can replicate themselves hundreds of times in one cell,’ said Matthew Taylor, first author on the study and a postdoctoral researcher in the laboaratory of Lynn Enquist, the Henry L boldenone-300.com/boldenone-300-side-effects .
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